Breast cancer can make anyone feel alone. The American Cancer Society is there for people every step of the way as they fight breast cancer by providing 24/7 phone support, rides to treatment, places to stay during treatment, or even just a hand to hold. Together, we are
stronger than breast cancer.
American Cancer Society Denim Day is October 6, 2017.
The American Cancer Society Denim Day – Oct 6, 2017 – brings us together to help save more lives from breast cancer. Since the event’s beginning in 1996, participants have raised more than $96 million to make sure no one has to face the disease alone.
Denim Day donations help us save more lives from breast cancer. Mortality rates from the disease have dropped 38% since 1989. That’s 297,300 fewer breast cancer deaths during that time! We’re making progress each and every day.
This year about 252,710 American women are expected to be diagnosed with breast cancer, while 40,610 women are expected to die from the disease. With deaths from the disease among women ranking second only to lung cancer in the United States, we must continue to make progress. The American Cancer Society issues breast
cancer screening guidelines, funds research for improved screening and treatment, encourages healthy lifestyles that can help prevent a diagnosis, and provides programs and services for all who face the disease.
Our mission is to save lives, celebrate lives,
and lead the fight for a world without cancer.
Your Denim Day donations will help us save more lives from breast cancer. We do the most for people with
breast cancer today, to end the disease tomorrow.
In fact, mortality rates from breast cancer have dropped 38% among women since 1989. That's 297,300 fewer breast cancer deaths during that time! Your support will help make it possible to end breast cancer once and for all.
Research to Find Causes, Better Treatments, and Cures for Breast Cancer The American Cancer Society has invested more than $4.6 billion in cancer research since 1946 and has played a role in nearly every cancer research breakthrough in recent history. In 2017, we continue to use donations from Denim Day to help fund breast cancer research, programs, and services. To find out more about projects we fund, CLICK HERE.
American Cancer Society DENIM DAY GRANT PROFILE SUMMARY
Stacey Finley, PhD
University of Southern California
Angiogenesis is the way in which a solid tumor generates its own blood supply, enabling the tumor to obtain the oxygen and nutrients needed for growth. Therefore, angiogenesis is a prominent target for cancer therapies; so far, however, these therapies have achieved limited success, particularly in breast cancer. The development of an effective antiangiogenic therapy requires a detailed understanding of the changing concentrations of proangiogenic and antiangiogenic factors, which determine the extent of blood vessel formation and thus the response following antiangiogenic therapy.
In her American Cancer Society grant application, Stacey Finley, PHD proposes to develop a computer-driven model of the molecules that stimulate and inhibit tumor angiogenesis. She will use the model to predict the effects of therapies that inhibit new angiogenesis. She will test the idea that a strong inhibition requires targeting both factors that inhibit proangiogenic activities and simultaneously those that mimic the action of antiangiogenic factors. As a result, a mathematical relationship between the concentrations of these angiogenic factors and the ability to grow new blood vessels will be established.
Finley’s model will be tested using human cancer cell lines and tumor cells generated from primary tumors. She will then simulate antiangiogenic therapies and predict their effects on the angiogenic response. Strategies predicted to effectively reduce the angiogenic response will be tested. The project will serve as a critical foundation for future mechanistic studies of angiogenesis in cancer patients.
The American Cancer Society Denim Day brings people together to help free the world from the pain and suffering of breast cancer.
In the weeks leading up to Denim Day, rally your friends and coworkers to donate $5 or more to wear jeans to work on Friday, October 6. Money raised will support the American Cancer Society’s work to save lives from breast cancer.
Since Denim Day began in 1996, participants have raised more than $96 million to help save lives from breast cancer.
This year, by joining together, we’ll add even more to that total. Donations will help the American Cancer Society fund groundbreaking breast cancer research; provide free, comprehensive information and support to those touched by breast cancer; and help people take steps to reduce their breast cancer risk or find it early when it's easier to treat.
History of Denim Day
Denim Day began with a simple concept – if each of us takes a small step to help eliminate breast cancer, collectively, those steps will take us far in achieving our goal. Employees at a private company got together to ask coworkers for donations to “go casual” for the cause. And what’s more casual than denim?
The idea spread, and now companies, schools, and other organizations nationwide have participated in raising funds and awareness to support our programs and services that help those with breast cancer, and also to help others avoid a diagnosis altogether.