The Clinic for Special Childrens approach to the care of patients with genetic disorders has wide medical relevance. Although we find “new” genetic disorders in the Amish and Mennonite populations, these disorders are not unique to the Plain populations. They are typical of genetic problems found throughout the world, problems which our clinical and laboratory experiences help solve. The Clinic is situated in the heart of Lancaster County, nestled between two Amish farms in Strasburg. The Clinic’s original timber frame building was “raised” in 1990 through generous contributions and volunteer community labor. An expansion was completed in 2001 to accommodate the growth of staff and services. Our staff includes three pediatric specialists and a PhD molecular geneticist. The Clinic operates as an independent, non-profit organization governed by a board of directors and supported through fees for services,proceeds from annual community-sponsored benefit auctions, and private contributions from individuals, organizations, and foundations. We are a registered charitable organization in Pennsylvania and tax-exempt under IRS 501(c)(3), ID # 23-2555373. Two-thirds of the Clinic’s operating budget relies on charitable contributions from individuals and foundations.