Frederik Hes via Crowdrise
November 01, 2011
BENEFITING: COLON CANCER CHALLENGE FOUNDATION
EVENT DATE: Nov 06, 2011
I’m a doctor specialized in hereditary colorectal cancer, and a dedicated marathon runner. By running the New York City marathon I want to raise money for hereditary colorectal cancer. This year, I’m the appointed runner for The International Society for Gastrointestinal Hereditary Tumours (InSiGHT, www.insight-group.org) that participates within the Human Variome Project (HVP). The HVP aims to collect all human genetic variation affecting health to a central resource that is freely available.
With the growing possibilities of genome analyses, we are faced with the problem of finding many DNA-variants with, as of yet, unknown clinical significance. Comparing variants found in patients and families worldwide will therefore greatly increase the knowledge of these variants, and thus help identifying genetic risk factor in colon cancer. Identifying genetic risk factor in colon cancer is important because it optimizes the timing and efficiency of surveillance (colonoscopy) and treatment (removal of polyps) in at-risk persons. In other words, sharing data is reducing disease.
We cooperate in this with the colon cancer challenge foundation (CCCF, www.coloncancerchallenge.org) that made a slot available for this InSiGHT/HVP initiative. CCCF is a not-for-profit organization registered in New York State as a public charity dedicated to reducing colon cancer incidence and death. Together we want to raise grants for young researchers who will be tasked with comparing and analyzing DNA-variants that are in drawers of research labs all around the world. As a start we want to realize Young Scholar Travel Awards. Each award represents a sum of $3,000 and these will be awarded in scientific meetings of InSiGHT.
Board of advisors
- Prof. Finlay Macrae, gastroenterologist and secretary of InSiGHT, Melbourne, Australia
- Dale L. Mintz, MPA, CHES, Executive Director, CCCF, New York, USA
- Dr. Thomas Weber, surgeon, member of InSiGHT and president of CCCF, New York, USA
- Prof. Richard Cotton, geneticist and founder of the Human Variome Project, Melbourne, Australia
- Prof. Johan den Dunnen, geneticist and head of the LOVD database, Leiden, Netherlands
- Luuk Kornelius, PhD, Director Business Innovation & Technology at Atlas Services Group, Netherlands
- Prof. Henry Lynch, MD, pioneer of hereditary cancer, Creighton Cancer Center, USA