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Heather DeBruin's Fundraiser:

Wade's Army

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Heather DeBruin

THE STORY:

In honor of Wade on what would be his 5th Birthday, Ella, Hadley, Crosby and I will for pediatric cancer awareness. Please help us turn awareness into action by donating in honor of Wade but more importantly, to help those that have a fighting chance.

As you know, Wade's Army is dedicated to funding phase 1 clinical trials. This year, the money raised will help initiate and support: Phase 1 clinical trial hu.14-18.IL2 in combination with ex-vivo expanded haploidentical NK cells for children with high-risk neuroblastoma.

That's the fancy title for an 18 person trial (or up to) at the University of Wisconsin. In short, and in very basic terms, this trial determine the safety and anti-tumor activity of administering multiple infusions of a laboratory expanded parent NK (Natural Killer) cell in conjunction with current anti-body treatment. Chemo will also be given to interrupt t-cell that interfere with anti-tumor response.
This approach may be effective in children with bulky tumor as well as minimal disease.

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